TOXICOLOGICAL INHALATION STUDIES IN RATS TO SUBSTANTIATE GROUPING OF ZINC OXIDE NANOFORMS


A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell lines

Abstract CRISPR prime-editors are emergent tools for genome editing and offer a versatile alternative approach to HDR-based genome engineering or DNA base-editors.However, sufficient prime-editor expression levels and availability of optimized transfection protocols may affect editing efficiencies, especially in hard-to-transfect cells like hiPSC.H

read more



Self-organization of intracellular gradients during mitosis

Abstract Gradients are used Pussy Pumps in a number of biological systems to transmit spatial information over a range of distances.The best studied are morphogen gradients where information is transmitted over many cell lengths.Smaller mitotic gradients reflect the need to organize several distinct events along the length of the mitotic spindle.Th

read more